BDBM50201927 3-hydroxy-2-phenylquinoline-4-carboxylic acid::CHEMBL219376
SMILES OC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1
InChI Key InChIKey=XAPRFLSJBSXESP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50201927
Affinity DataIC50: 6.50E+6nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKd: 1.50E+4nMAssay Description:Binding affinity to human PDE10A catalytic domain expressed in Escherichia coli BL21-Gold(DE3) after 15 mins by SPR inhibition in solution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+6nMAssay Description:Inhibition of P-selectin-mediated adhesion of HL60 cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair