BDBM50201927 3-hydroxy-2-phenylquinoline-4-carboxylic acid::CHEMBL219376

SMILES OC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=XAPRFLSJBSXESP-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201927   

TargetP-selectin(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataIC50:  6.50E+6nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to human PDE10A catalytic domain expressed in Escherichia coli BL21-Gold(DE3) after 15 mins by SPR inhibition in solution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin glycoprotein ligand 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataIC50:  6.00E+6nMAssay Description:Inhibition of P-selectin-mediated adhesion of HL60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed