BDBM50202277 (S)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-3-phenylpropanoic acid::2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]-3-phenylpropanoic acid::CHEMBL243190::Thiazolidinone core, 24
SMILES OC(=O)[C@H](Cc1ccccc1)N1C(=S)S\C(=C/c2ccc(Br)cc2)C1=O
InChI Key InChIKey=NWNRPXAZPNUBGV-CNYBTUBUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50202277
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
University Of Minnesota Minneapolis
Curated by ChEMBL
University Of Minnesota Minneapolis
Curated by ChEMBL
Affinity DataKi: 5.25E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
Affinity DataKi: 1.42E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.42E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl2More data for this Ligand-Target Pair
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota Minneapolis
Curated by ChEMBL
University Of Minnesota Minneapolis
Curated by ChEMBL
Affinity DataKi: 2.15E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Minnesota Minneapolis
Curated by ChEMBL
University Of Minnesota Minneapolis
Curated by ChEMBL
Affinity DataKi: 2.15E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nM Kd: 9.30E+3nMAssay Description:To access the ability of compounds to inhibit the catalytic activity of UGM, an HPLC assay was employed. Inhibition constants were determined by mon...More data for this Ligand-Target Pair
Affinity DataKd: >3.30E+4nMAssay Description:To access the ability of compounds to inhibit the catalytic activity of UGM, an HPLC assay was employed. Inhibition constants were determined by mon...More data for this Ligand-Target Pair