BDBM50202380 (RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]piperidine::(RS/SR)-2-[1-(4-isopropylphenyl)-3-methylbutyl]piperidine::CHEMBL218193

SMILES CC(C)CC(C1CCCCN1)c1ccc(cc1)C(C)C

InChI Key InChIKey=OYPZJIHQZRPSNC-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50202380   

TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataKi: >6.50E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202380((RR/SS)-2-[1-(4-isopropylphenyl)-3-methylbutyl]pip...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed