BDBM50202399 (RR/SS)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperidine::(RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperidine::CHEMBL373773

SMILES Clc1ccc(cc1)C(Cc1ccccc1)C1CCCCN1

InChI Key InChIKey=SOCRIYWOGGANHT-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50202399   

TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataIC50: 370nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataIC50: 390nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataKi:  440nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataKi:  440nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202399BDBM50202399((RS/SR)-2-[1-(4-chlorophenyl)-2-phenylethyl]piperi...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed