BDBM50202403 1-phenyl-1-(piperidin-2-yl)propan-2-one::CHEMBL219540

SMILES CC(=O)C(C1CCCCN1)c1ccccc1

InChI Key InChIKey=IYNBYQDXVFMDGE-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50202403   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202403(1-phenyl-1-(piperidin-2-yl)propan-2-one | CHEMBL21...)
Affinity DataKi:  370nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202403(1-phenyl-1-(piperidin-2-yl)propan-2-one | CHEMBL21...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202403(1-phenyl-1-(piperidin-2-yl)propan-2-one | CHEMBL21...)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202403(1-phenyl-1-(piperidin-2-yl)propan-2-one | CHEMBL21...)
Affinity DataIC50:  190nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202403(1-phenyl-1-(piperidin-2-yl)propan-2-one | CHEMBL21...)
Affinity DataIC50: >9.70E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202403(1-phenyl-1-(piperidin-2-yl)propan-2-one | CHEMBL21...)
Affinity DataIC50:  220nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed