BDBM50202549 CHEMBL3951052

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nccc(-c3ccc(CN4CCN(CCO)CC4)cc3)c2c1

InChI Key InChIKey=PVMLGIUZPIXOHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202549   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50202549(CHEMBL3951052)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed