BDBM50203188 2-((1r,4r)-4-(4-chlorophenyl)cyclohexyl)-3-hydroxynaphthalene-1,4-dione::2-[4-(4-Chloro-phenyl)-cyclohexyl]-3-hydroxy-[1,4]naphthoquinone::2-[4-(4-Chloro-phenyl)-cyclohexyl]-3-hydroxy-[1,4]naphthoquinone(atovaquone)::3-(4-(4-chlorophenyl)cyclohexyl)-4-hydroxynaphthalene-1,2-dione::566C::566C80::ATOVAQUONE::CHEMBL1450::Mepron::trans-3-(4-(4-chlorophenyl)cyclohexyl)-1,4-dihydronaphthalene-1,2,4-triol

SMILES: Clc1ccc(cc1)[C@H]1CC[C@@H](CC1)C1C(=O)C(=O)c2ccccc2C1=O

InChI Key: InChIKey=UYFLKEIEOREOFC-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50203188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Blood fluke)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	432	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Blood fluke)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (malaria parasite P. falciparum)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (fumarate) (Baker's yeast)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Rat)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50203188 (CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair