BDBM50203996 (+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine trihydrochloride::CHEMBL536747

SMILES CC(C)N1CCC(CC1)C(CN1CCN(CCCc2c(F)cccc2-c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=DHUKBDYVZDFTNL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50203996   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  491nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  723nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  18.3nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed