BDBM50204072 CHEMBL3945199::US10543183, Compound 12::US10945978, Compound 12

SMILES: CC(C)(c1cn(c(n1)C(C)(C)c2c(cccc2Cl)Cl)c3ccc(cc3F)c4cc(c(c(c4)S(=O)(=O)C)CO)F)O

InChI Key: InChIKey=HNAJDMYOTDNOBK-UHFFFAOYSA-N

Data: 2 KI  1 IC50  10 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50204072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha (Human)	BDBM50204072 (CHEMBL3945199 | US10543183, Compound 12 | US109459...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair