BDBM50204294 CHEMBL3943295::US20230295171, Example 8
SMILES Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)nc3CNC(=O)c23)c1
InChI Key InChIKey=VPNLOOYVNORYBV-UONOGXRCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50204294
Affinity DataEC50: 35nMAssay Description:Inhibition of SYK in TgM-stimulated human Ramos cells expressing RA1/GFP-tagged BLNK assessed as reduction in RA1/GFP-tagged BLNK phosphorylation pre...More data for this Ligand-Target Pair
Affinity DataIC50: 7.94nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
Affinity DataIC50: 7.94nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human C-terminal 6His-tagged SYK (356 to 635 residues) expressed in Sf9 insect cells using 5-carboxyfluorescein(FAM)-EEPLYWSFPAKKK-NH2 ...More data for this Ligand-Target Pair