BDBM50204475 1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one::CHEMBL373555

SMILES Brc1cnc(o1)C(=O)CCCCCCc1ccccc1

InChI Key InChIKey=DMKFBAZOWIRQSU-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50204475   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204475(1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one | CHEM...)
Affinity DataKi:  3nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204475(1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one | CHEM...)
Affinity DataKi:  3nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50204475(1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one | CHEM...)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204475(1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one | CHEM...)
Affinity DataIC50:  190nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204475(1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one | CHEM...)
Affinity DataIC50:  100nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204475(1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one | CHEM...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed