BDBM50204570 1-(5-(2-fluorophenyl)oxazol-2-yl)-7-phenylheptan-1-one::CHEMBL223693

SMILES Fc1ccccc1-c1cnc(o1)C(=O)CCCCCCc1ccccc1

InChI Key InChIKey=VNIXKUPUOKDAMU-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50204570   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204570(1-(5-(2-fluorophenyl)oxazol-2-yl)-7-phenylheptan-1...)
Affinity DataKi:  110nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204570(1-(5-(2-fluorophenyl)oxazol-2-yl)-7-phenylheptan-1...)
Affinity DataKi:  110nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50204570(1-(5-(2-fluorophenyl)oxazol-2-yl)-7-phenylheptan-1...)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed