BDBM50204587 (S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine::CHEMBL247479
SMILES CN(C)CCOc1ccc(cc1)-c1oc2ncnc(NC[C@@H]3CCCO3)c2c1-c1ccccc1
InChI Key InChIKey=XNSZHQUDPHATEN-QFIPXVFZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50204587
Affinity DataKi: 5nMAssay Description:Inhibition of N-terminal His6-tagged ACK1 expressed in baculovirus infected Hi5 cells assessed as inhibition of autophosphorylation after 2 hrs by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of ACK1 in mouse C8 cells assessed as decrease in cell viability after 20 to 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair