BDBM50204694 3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL)-1,4-DIHYDROINDENO[1,2-C]PYRAZOLE-6-CARBOXAMIDE::3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,2-c]pyrazole-6-carboxylic acid (trans-4-hydroxycyclohexyl)-amide::3-(4'-hydroxybiphenyl-4-yl)-N-((1r,4r)-4-hydroxycyclohexyl)-1,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide::3-(4'-hydroxybiphenyl-4-yl)-N-(trans-4-hydroxycyclohexyl)-2,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide::CHEMBL438485

SMILES: O[C@H]1CC[C@@H](CC1)NC(=O)c1ccc-2c(Cc3c(n[nH]c-23)-c2ccc(cc2)-c2ccc(O)cc2)c1

InChI Key: InChIKey=VKPCXCHYSBVEMW-UHFFFAOYSA-N

Data: 1 KI  17 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50204694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Sgk1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.90E+4	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Sgk1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C delta type (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C gamma type (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk2 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MARK2 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.52E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50204694 (3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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