BDBM50204710 (1r,4r)-N-((3-(4-(aminomethyl)phenyl)-1,4-dihydroindeno[1,2-c]pyrazol-6-yl)methyl)-4-methylcyclohexanamine::CHEMBL428392

SMILES C[C@H]1CC[C@@H](CC1)NCc1ccc-2c(Cc3c(n[nH]c-23)-c2ccc(CN)cc2)c1

InChI Key InChIKey=PWBSAEUXFXJHPK-OQIWPSSASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50204710   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50204710((1r,4r)-N-((3-(4-(aminomethyl)phenyl)-1,4-dihydroi...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of recombinant CHK1 assessed as human Cdc25C phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed