BDBM50204832 4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N-(3-(2-oxopyrrolidin-1-yl)propyl)nicotinamide::CHEMBL234655

SMILES Fc1ccc(Br)cc1-c1nc(Nc2ccncc2C(=O)NCCCN2CCCC2=O)c2nccnc2n1

InChI Key InChIKey=GZOYOEIHAGHGFM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50204832   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  123nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed