BDBM50204898 (6-hydroxy-1H-indole-2-yl)-(4-phenoxypiperidine)-methanone::CHEMBL426731

SMILES Oc1ccc2cc([nH]c2c1)C(=O)N1CCC(CC1)Oc1ccccc1

InChI Key InChIKey=PLLMNEPTGHLYBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204898   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204898((6-hydroxy-1H-indole-2-yl)-(4-phenoxypiperidine)-m...)
Affinity DataIC50:  89nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204898((6-hydroxy-1H-indole-2-yl)-(4-phenoxypiperidine)-m...)
Affinity DataIC50:  107nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed