BDBM50205661 4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-yl)methoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine::CHEMBL247669
SMILES CC(C)N1CCC(COc2cc3CNCC(c4ccc(Cl)c(Cl)c4)c3cn2)CC1
InChI Key InChIKey=CQWSBUJEGUSBFA-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50205661
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair