BDBM50205661 4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-yl)methoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine::CHEMBL247669

SMILES CC(C)N1CCC(COc2cc3CNCC(c4ccc(Cl)c(Cl)c4)c3cn2)CC1

InChI Key InChIKey=CQWSBUJEGUSBFA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205661   

TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205661(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  13nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205661(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  18nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205661(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  37nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed