BDBM50205745 (3S,6S,9R,12S,15S,23S)-15-[(2S)-2-aminohexanamido]-6-(3-carbamimidamidopropyl)-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide::CHEMBL393075
SMILES CCCC[C@H](N)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O
InChI Key InChIKey=ZPANOUCVWZTSLE-VIONFHLBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50205745
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Effect on human MC3R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Effect on human MC5R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Vrije Universiteit Brussel
Curated by ChEMBL
Vrije Universiteit Brussel
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:Effect on human MC4R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Vrije Universiteit Brussel
Curated by ChEMBL
Vrije Universiteit Brussel
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Effect on human MC1R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair