BDBM50206063 4-(4-{6-[(thiophene-2-carboximidoyl)-amino]-benzothiazol-2-ylamino}-piperidin-1-ylmethyl)-benzoic acid::CHEMBL234499

SMILES NC(=Nc1ccc2nc(NC3CCN(Cc4ccc(cc4)C(O)=O)CC3)sc2c1)c1cccs1

InChI Key InChIKey=RDEJBAAVSOBTGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206063   

TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206063(4-(4-{6-[(thiophene-2-carboximidoyl)-amino]-benzot...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of human endothelial NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206063(4-(4-{6-[(thiophene-2-carboximidoyl)-amino]-benzot...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human neuronal NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206063(4-(4-{6-[(thiophene-2-carboximidoyl)-amino]-benzot...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human inducible NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed