BDBM50206120 3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)-4-(pyridin-2-ylmethylamino)pyridin-2(1H)-one::3-[5-(1H-IMIDAZOL-1-YL)-7-METHYL-1H-BENZIMIDAZOL-2-YL]-4-[(PYRIDIN-2-YLMETHYL)AMINO]PYRIDIN-2(1H)-ONE::CHEMBL397666

SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCc2ccccn2)cc[nH]c1=O)-n1ccnc1

InChI Key InChIKey=GLTRPHMPCVLOJS-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50206120   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206120(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant IGF1 receptorMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206120(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206120(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of CYP2D6 in microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206120(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)
Affinity DataIC50:  80nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed