BDBM50206280 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-morpholinoethyl)phenyl)pyrimidin-2-amine::4-ARYL-2-PHENYLAMINO PYRIMIDINE::CHEMBL233209

SMILES CC(C)(N)c1ccc(cc1)-c1nc(Nc2ccc(CCN3CCOCC3)cc2)ncc1Cl

InChI Key InChIKey=CJSSYVIHFXDFFC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206280   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  148nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed