BDBM11162 (1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorobenzyl)propylamine::(3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[3,4-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride::CHEMBL393336::MK-0431::Sitagliptin::Sitagliptin (13)::Triazolopiperazine Analogue 1::US10479798, Compound MK0431

SMILES: N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=MFFMDFFZMYYVKS-UHFFFAOYSA-N

Data: 7 KI  176 IC50  4 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 187 hits for monomerid = 11162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 [K6R,T557I] (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.48E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neprilysin (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Mouse)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Rat)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aminopeptidase N (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase IV (Porphyromonas gingivalis)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Bovine)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.47E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Mouse)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 (Rat)	BDBM11162 (Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair