BDBM50207324 CHEMBL3898125
SMILES Cn1c(Nc2c(F)cccc2Cl)nc2cc(C(=O)Nc3ccc(F)c(c3)C(F)(F)F)c3OCCOc3c12
InChI Key InChIKey=MRUCMCCYXQYKGZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50207324
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGE2 production preincubated followed by LPS stimulation for 20 to 24...More data for this Ligand-Target Pair