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BDBM50207993 3-(1-(4-imidazolylmethyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one::CHEMBL223022

SMILES: O=C1NC(CN1C1CCN(Cc2cnc[nH]2)CC1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=RRHMCEJLGKCOGL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207993   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50207993
PNG
(3-(1-(4-imidazolylmethyl)-piperidin-4-yl)-5,5-diph...)
Show SMILES O=C1NC(CN1C1CCN(Cc2cnc[nH]2)CC1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H27N5O/c30-23-27-24(19-7-3-1-4-8-19,20-9-5-2-6-10-20)17-29(23)22-11-13-28(14-12-22)16-21-15-25-18-26-21/h1-10,15,18,22H,11-14,16-17H2,(H,25,26)(H,27,30)
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Article
PubMed
1.06E+3n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHO K1 cells


J Med Chem 50: 1571-83 (2007)


Article DOI: 10.1021/jm061159a
BindingDB Entry DOI: 10.7270/Q2QV3M61
More data for this
Ligand-Target Pair