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BDBM50208125 5-ethyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid::CHEMBL436301

SMILES: CCC1(OC(=CC1=O)C(O)=O)c1ccccc1

InChI Key: InChIKey=SUHZZFNDVLWPTL-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208125   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50208125
PNG
(5-ethyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxy...)
Show SMILES CCC1(OC(=CC1=O)C(O)=O)c1ccccc1
Show InChI InChI=1S/C13H12O4/c1-2-13(9-6-4-3-5-7-9)11(14)8-10(17-13)12(15)16/h3-8H,2H2,1H3,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2.40E+4n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Activity at GPR109a in CHO cells assessed as inhibition of forskolin-induced cAMP generation


J Med Chem 50: 1445-8 (2007)


Article DOI: 10.1021/jm070022x
BindingDB Entry DOI: 10.7270/Q2BK1C1Z
More data for this
Ligand-Target Pair
HM74 nicotinic acid GPCR


(Homo sapiens (Human))
BDBM50208125
PNG
(5-ethyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxy...)
Show SMILES CCC1(OC(=CC1=O)C(O)=O)c1ccccc1
Show InChI InChI=1S/C13H12O4/c1-2-13(9-6-4-3-5-7-9)11(14)8-10(17-13)12(15)16/h3-8H,2H2,1H3,(H,15,16)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 4.80E+3n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation


J Med Chem 50: 1445-8 (2007)


Article DOI: 10.1021/jm070022x
BindingDB Entry DOI: 10.7270/Q2BK1C1Z
More data for this
Ligand-Target Pair