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BDBM50208199 CHEMBL3884844

SMILES: CN(C)CCCOc1nc2ccccc2c2nc3ccccc3nc12

InChI Key: InChIKey=AXPXYVKHVZFRON-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50208199   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Topoisomerase II alpha (HuTopoIIα)


(Homo sapiens (Human))
BDBM50208199
PNG
(CHEMBL3884844)
Show SMILES CN(C)CCCOc1nc2ccccc2c2nc3ccccc3nc12
Show InChI InChI=1S/C20H20N4O/c1-24(2)12-7-13-25-20-19-18(14-8-3-4-9-15(14)23-20)21-16-10-5-6-11-17(16)22-19/h3-6,8-11H,7,12-13H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.38E+4n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of human DNA topoisomerase 2alpha-mediated decatenation of kinetoplast DNA after 60 mins by agarose gel electrophoresis


Eur J Med Chem 123: 704-717 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.063
BindingDB Entry DOI: 10.7270/Q2TQ63HJ
More data for this
Ligand-Target Pair