BDBM50208260 CHEMBL3884988

SMILES O=S(=O)(c1ccccc1)n1ccc2c(cccc12)N1CCN(CCNc2c3CCCCc3nc3ccccc23)CC1

InChI Key InChIKey=HFXNFOSTKCPMIS-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50208260   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University Collegium Medicum

Curated by ChEMBL
LigandPNGBDBM50208260(CHEMBL3884988)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in CHOK1 cell membranes measured after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Jagiellonian University Collegium Medicum

Curated by ChEMBL
LigandPNGBDBM50208260(CHEMBL3884988)
Affinity DataIC50:  44nMAssay Description:Inhibition of human recombinant AChE preincubated for 5 mins followed by acetylthiocholine iodide substrate addition measured after 5 mins by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Jagiellonian University Collegium Medicum

Curated by ChEMBL
LigandPNGBDBM50208260(CHEMBL3884988)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of electric eel AChE preincubated for 5 mins followed by acetylthiocholine iodide substrate addition measured after 5 mins by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Jagiellonian University Collegium Medicum

Curated by ChEMBL
LigandPNGBDBM50208260(CHEMBL3884988)
Affinity DataIC50:  17nMAssay Description:Inhibition of equine serum BuChE preincubated for 5 mins followed by butyrylthiocholine iodide substrate addition measured after 5 mins by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed