BDBM50208517 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one::CHEMBL222102::KU-55933

SMILES: c1ccc2c(c1)Sc3cccc(c3S2)C4=CC(=O)C=C(O4)N5CCOCC5

InChI Key: InChIKey=XRKYMMUGXMWDAO-UHFFFAOYSA-N

Data: 1 KI  22 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50208517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ATR (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	458	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ATR (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM50208517 (KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair