BDBM50208574 (R)-3-((2-benzyl-6-((3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl)pyridin-3-yl)ethynyl)quinuclidin-3-ol::(R)-3-(2-(2-benzyl-6-((3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl)pyridin-3-yl)ethynyl)quinuclidin-3-ol::CHEMBL258717

SMILES CO[C@H]1CN(C[C@H]1O)c1ccc(C#C[C@@]2(O)CN3CCC2CC3)c(Cc2ccccc2)n1

InChI Key InChIKey=NDEOTZXSBKCQLS-RMTZWNOUSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208574   

TargetSqualene synthase(Homo sapiens (Human))
Instituto De Parasitolog£A Y Biomedicina&Quot;L£Pez-Neyra

Curated by ChEMBL
LigandPNGBDBM50208574((R)-3-((2-benzyl-6-((3R,4S)-3-hydroxy-4-methoxypyr...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant squalene synthaseMore data for this Ligand-Target Pair
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50208574((R)-3-((2-benzyl-6-((3R,4S)-3-hydroxy-4-methoxypyr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed