BDBM50209010 3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)-benzenesulfonamide::CHEMBL399379

SMILES COc1ccc(cc1NS(=O)(=O)c1cc(Cl)cc(Cl)c1O)-c1ccccc1

InChI Key InChIKey=SIIPNDKXZOTLEA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50209010   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209010(3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209010(3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209010(3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...)
Affinity DataIC50:  442nMAssay Description:Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209010(3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...)
Affinity DataIC50:  377nMAssay Description:Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209010(3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed