BDBM50209188 6-(2-Hydroxy-phenyl)-2-oxo-4-phenyl-1,2-dihydro-pyridine-3-carbonitrile::6-(2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile::CHEMBL441913

SMILES Oc1ccccc1-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1

InChI Key InChIKey=LLBAPJVAKZDUIA-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209188   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50209188(6-(2-Hydroxy-phenyl)-2-oxo-4-phenyl-1,2-dihydro-py...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Pim-1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate preincubated for 15 mins prior substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209188(6-(2-Hydroxy-phenyl)-2-oxo-4-phenyl-1,2-dihydro-py...)
Affinity DataKd:  7.50E+4nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed