BDBM50209363 CHEMBL228275::cyclopentyl(4-(4-(6-(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)methanone

SMILES COCCOc1ccc2ncnc(Nc3ccc(OC4CCN(CC4)C(=O)C4CCCC4)c(C)c3)c2c1

InChI Key InChIKey=LGZNBXZSMPAJEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209363   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209363(cyclopentyl(4-(4-(6-(2-methoxyethoxy)quinazolin-4-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209363(cyclopentyl(4-(4-(6-(2-methoxyethoxy)quinazolin-4-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed