BDBM50209506 CHEMBL266212::N-(2-(4-(4-(3,4-dimethoxybenzyl)piperazin-1-yl)phenylcarbamoyl)phenyl)quinoline-3-carboxamide
SMILES COc1ccc(CN2CCN(CC2)c2ccc(NC(=O)c3ccccc3NC(=O)c3cnc4ccccc4c3)cc2)cc1OC
InChI Key InChIKey=LYPHFRXCVAZTEC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50209506
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2A6 expressed in insect microsome after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human CYP3A4 expressed in insect microsome using 7-benzyloxy-4-trifluoromethylcoumarin substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2B6 expressed in insect microsome after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 expressed in insect microsome after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2E1 expressed in insect microsome after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human CYP2C8 expressed in insect microsome after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human CYP2C19 expressed in insect microsome after 30 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 124nMAssay Description:Reversal of P-gp-mediated multidrug resistance to vinblastine in human CEM/VLB500 cells after 3 days by resazurin assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2D6 expressed in insect microsome after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 expressed in insect microsome after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of human CYP2E1 expressed in insect microsome using 7-benzyloxyquinoline substrate after 30 minsMore data for this Ligand-Target Pair