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BDBM50209661 CHEMBL226713::[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methoxy})phosphinic acid

SMILES: OC[C@H]1O[C@](O)(COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=HIDNNWOFQMQOHD-HWEKWTFHSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209661   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purinergic receptor P2Y14


(Homo sapiens (Human))
BDBM50209661
PNG
(CHEMBL226713 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
Show SMILES OC[C@H]1O[C@](O)(COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-6-10(21)12(23)15(25,33-6)5-31-36(28,29)34-35(26,27)30-4-7-9(20)11(22)13(32-7)17-2-1-8(19)16-14(17)24/h1-2,6-7,9-13,18,20-23,25H,3-5H2,(H,26,27)(H,28,29)(H,16,19,24)/t6-,7-,9-,10-,11-,12+,13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 880n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
Purinergic receptor P2Y14


(Homo sapiens (Human))
BDBM50209661
PNG
(CHEMBL226713 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
Show SMILES OC[C@H]1O[C@](O)(COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-6-10(21)12(23)15(25,33-6)5-31-36(28,29)34-35(26,27)30-4-7-9(20)11(22)13(32-7)17-2-1-8(19)16-14(17)24/h1-2,6-7,9-13,18,20-23,25H,3-5H2,(H,26,27)(H,28,29)(H,16,19,24)/t6-,7-,9-,10-,11-,12+,13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 880n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair