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BDBM50209854 CHEMBL3884634

SMILES: O=c1cc(ncn1CCCCCN1CCN(Cc2ccccc2)CC1)-c1ccccc1

InChI Key: InChIKey=ZNABTQZRXWSHES-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209854   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50209854
PNG
(CHEMBL3884634)
Show SMILES O=c1cc(ncn1CCCCCN1CCN(Cc2ccccc2)CC1)-c1ccccc1
Show InChI InChI=1S/C26H32N4O/c31-26-20-25(24-12-6-2-7-13-24)27-22-30(26)15-9-3-8-14-28-16-18-29(19-17-28)21-23-10-4-1-5-11-23/h1-2,4-7,10-13,20,22H,3,8-9,14-19,21H2
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UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
772n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHOK1 cell membranes after 1 hr by liquid scintillation counting m...


Bioorg Med Chem 25: 1250-1259 (2017)


Article DOI: 10.1016/j.bmc.2016.12.039
BindingDB Entry DOI: 10.7270/Q25T3NH5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50209854
PNG
(CHEMBL3884634)
Show SMILES O=c1cc(ncn1CCCCCN1CCN(Cc2ccccc2)CC1)-c1ccccc1
Show InChI InChI=1S/C26H32N4O/c31-26-20-25(24-12-6-2-7-13-24)27-22-30(26)15-9-3-8-14-28-16-18-29(19-17-28)21-23-10-4-1-5-11-23/h1-2,4-7,10-13,20,22H,3,8-9,14-19,21H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.33E+3n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from recombinant human 5-HT7A receptor expressed in CHOK1 cell membranes after 40 mins by liquid scintillation counting met...


Bioorg Med Chem 25: 1250-1259 (2017)


Article DOI: 10.1016/j.bmc.2016.12.039
BindingDB Entry DOI: 10.7270/Q25T3NH5
More data for this
Ligand-Target Pair