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BDBM50209856 CHEMBL3885178

SMILES: Cc1nc2ccccc2c(=O)n1CCCCCN1CCN(CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=POPGMXCMNWFNGG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209856   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50209856
PNG
(CHEMBL3885178)
Show SMILES Cc1nc2ccccc2c(=O)n1CCCCCN1CCN(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H29ClN4O/c1-19-26-23-8-4-3-7-22(23)24(30)29(19)14-6-2-5-13-27-15-17-28(18-16-27)21-11-9-20(25)10-12-21/h3-4,7-12H,2,5-6,13-18H2,1H3
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHOK1 cell membranes after 1 hr by liquid scintillation counting m...


Bioorg Med Chem 25: 1250-1259 (2017)


Article DOI: 10.1016/j.bmc.2016.12.039
BindingDB Entry DOI: 10.7270/Q25T3NH5
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50209856
PNG
(CHEMBL3885178)
Show SMILES Cc1nc2ccccc2c(=O)n1CCCCCN1CCN(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H29ClN4O/c1-19-26-23-8-4-3-7-22(23)24(30)29(19)14-6-2-5-13-27-15-17-28(18-16-27)21-11-9-20(25)10-12-21/h3-4,7-12H,2,5-6,13-18H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
327n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from recombinant human 5-HT7A receptor expressed in CHOK1 cell membranes after 40 mins by liquid scintillation counting met...


Bioorg Med Chem 25: 1250-1259 (2017)


Article DOI: 10.1016/j.bmc.2016.12.039
BindingDB Entry DOI: 10.7270/Q25T3NH5
More data for this
Ligand-Target Pair