BDBM50210032 ((2R,5S)-1-(4-chlorophenylsulfonyl)-5-phenylpyrrolidin-2-yl)methyl 4-(2-hydroxyethyl)piperazine-1-carboxylate::CHEMBL231448

SMILES OCCN1CCN(CC1)C(=O)OC[C@H]1CC[C@H](N1S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=XEFMRJOPPTYVAW-GGAORHGYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210032   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50210032(((2R,5S)-1-(4-chlorophenylsulfonyl)-5-phenylpyrrol...)
Affinity DataIC50:  540nMAssay Description:Inhibition of gamma-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed