BDBM50210046 ((2R,5S)-1-(4-chlorophenylsulfonyl)-5-phenylpyrrolidin-2-yl)methyl 4-methylpiperazine-1-carboxylate::CHEMBL396542

SMILES CN1CCN(CC1)C(=O)OC[C@H]1CC[C@H](N1S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=KJPZPMJTOPGUTG-IRLDBZIGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210046   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50210046(((2R,5S)-1-(4-chlorophenylsulfonyl)-5-phenylpyrrol...)
Affinity DataIC50:  450nMAssay Description:Inhibition of gamma-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed