BDBM50210360 CHEMBL234096::N-(2-((4-cyano-4-(2-(trifluoromethyl)phenyl)cyclohexyl)methylamino)pyridin-3-yl)-3,3,3-trifluoropropanamide

SMILES FC(F)(F)CC(=O)Nc1cccnc1NCC1CCC(CC1)(C#N)c1ccccc1C(F)(F)F

InChI Key InChIKey=KWCVJAURCBEMIX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210360   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50210360(CHEMBL234096 | N-(2-((4-cyano-4-(2-(trifluoromethy...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity at human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50210360(CHEMBL234096 | N-(2-((4-cyano-4-(2-(trifluoromethy...)
Affinity DataIC50:  1.15nMAssay Description:Antagonist activity in human bradykinin B1 receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed