BDBM50210638 1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::CHEMBL234447

SMILES C[C@@H]1CN(CCN1CCC1OCCc2cc(ccc12)C(N)=O)c1cccc2cc(F)ccc12

InChI Key InChIKey=BVWYBVKUPUODDY-QOBPCVTDSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210638   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210638(1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpipe...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210638(1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpipe...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in rat caudate membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210638(1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpipe...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]GR125743 from human 5HT1D expressed in LM(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50210638(1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpipe...)
Affinity DataKi:  281nMAssay Description:Displacement of [3H]GR125743 from human 5HT1B expressed in LM(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed