BDBM50210810 2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-purin-6-one::CHEMBL405761::N2-(3-trifluoromethylphenyl)guanine

SMILES FC(F)(F)c1cccc(Nc2nc3nc[nH]c3c(=O)[nH]2)c1

InChI Key InChIKey=IOWPKEYIXBBDOQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50210810   

TargetThymidine kinase(Human herpesvirus 2)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  151nMAssay Description:Inhibitory activity against HSV-1 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  150nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Macacine herpesvirus 1)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Herpes B virus recombinant thymidine kinase-mediated [3H]TdR phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  150nMAssay Description:Inhibition of HSV-1 thymidine kinase, 1 microM [3H]-thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 microM [3H]-thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  100nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed