BDBM50211259 CHEMBL3934441

SMILES O=C(N1CCCC[C@H]1Cc1ccccc1)n1cc(nn1)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=JKJMWHULJIOKPJ-VWLOTQADSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211259   

TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211259(CHEMBL3934441)
Affinity DataIC50:  631nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211259(CHEMBL3934441)
Affinity DataIC50:  794nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211259(CHEMBL3934441)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211259(CHEMBL3934441)
Affinity DataIC50:  631nMAssay Description:Inhibition of MB064 probe binding to DAGLalpha in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed