BDBM50211319 CHEMBL233623::N-((1r,4r)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2-methoxy-5-methylbenzenesulfonamide

SMILES COc1ccc(C)cc1S(=O)(=O)N[C@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccc1OC(C)C

InChI Key InChIKey=CHYHMJYTWVQCFW-YHBQERECSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211319   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50211319(CHEMBL233623 | N-((1r,4r)-4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human cloned adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50211319(CHEMBL233623 | N-((1r,4r)-4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human cloned adrenergic alpha1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50211319(CHEMBL233623 | N-((1r,4r)-4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  50nMAssay Description:Binding affinity to human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50211319(CHEMBL233623 | N-((1r,4r)-4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  218nMAssay Description:Binding affinity to human cloned adrenergic alpha1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed