BDBM50211369 Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys10)-NH2::CHEMBL2371969

SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(C)C

InChI Key InChIKey=IQSWKOJGUWKVIB-INCJRZKESA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50211369   

TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211369(Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at human MC5R expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211369(Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)
Affinity DataEC50:  330nMAssay Description:Agonist activity at human melanocortin receptor 1b expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211369(Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)
Affinity DataIC50:  4.90E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211369(Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211369(Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)
Affinity DataIC50:  4.70E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211369(Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed