BDBM50211431 4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-ylamino)-N-ethylpiperidine-1-carboxamide::CHEMBL248370

SMILES: CCNC(=O)N1CCC(CC1)Nc1ncc(C#N)c(n1)-c1c[nH]c2cc(F)ccc12

InChI Key: InChIKey=XVLIRDXMQGPGCW-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Human)	BDBM50211431 (4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50211431 (4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50211431 (4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
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Transcription factor Jun (Human)	BDBM50211431 (4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50211431 (4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair