BDBM50212122 (1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]methyl}-3-[(1S,5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]-1-[(methylsulfanyl)methyl]cyclopentane-1-carboxamide::CHEMBL231246
SMILES CSC[C@@]1(CC[C@H](C1)N1CC[C@]2(C=Cc3ccccc23)[C@@H](C)C1)C(=O)NCc1cc(F)cc(c1)C(F)(F)F
InChI Key InChIKey=CBXVNXOAKIFVRY-DAORKYKSSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50212122
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair