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BDBM50212166 7-chloro-6H-chromeno[4,3-b]quinoline-3,9-diol::CHEMBL402491

SMILES: Oc1ccc-2c(OCc3c(Cl)c4cc(O)ccc4nc-23)c1

InChI Key: InChIKey=RYBHKLZSHRZGQK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212166   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Estrogen-related receptor alpha


(Homo sapiens (Human))
BDBM50212166
PNG
(7-chloro-6H-chromeno[4,3-b]quinoline-3,9-diol | CH...)
Show SMILES Oc1ccc-2c(OCc3c(Cl)c4cc(O)ccc4nc-23)c1
Show InChI InChI=1S/C16H10ClNO3/c17-15-11-5-8(19)2-4-13(11)18-16-10-3-1-9(20)6-14(10)21-7-12(15)16/h1-6,19-20H,7H2
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human ERalpha


Bioorg Med Chem Lett 17: 4053-6 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV
More data for this
Ligand-Target Pair
Estrogen-related receptor beta


(Homo sapiens (Human))
BDBM50212166
PNG
(7-chloro-6H-chromeno[4,3-b]quinoline-3,9-diol | CH...)
Show SMILES Oc1ccc-2c(OCc3c(Cl)c4cc(O)ccc4nc-23)c1
Show InChI InChI=1S/C16H10ClNO3/c17-15-11-5-8(19)2-4-13(11)18-16-10-3-1-9(20)6-14(10)21-7-12(15)16/h1-6,19-20H,7H2
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 88n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human ERbeta


Bioorg Med Chem Lett 17: 4053-6 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV
More data for this
Ligand-Target Pair