BDBM50212323 (3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-hexahydrocyclopenta[c]furan-1-one::BAY36-7620::Bay 36-7620::CHEMBL254372

SMILES C=C1C[C@@H]2COC(=O)[C@]2(Cc2ccc3ccccc3c2)C1

InChI Key InChIKey=CVIRWLJKDBYYOG-MJGOQNOKSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50212323   

TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataKi:  11.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataKi:  140nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataKi:  240nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed