BDBM50212682 2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-methoxyphenyl)-4,5-dihydro-1H-imidazole::CHEMBL397784

SMILES COc1ccccc1C1CNC(=N1)c1ccc(OC(F)(F)F)c(Cl)c1

InChI Key InChIKey=HBZSFLJFXKNCOR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212682   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212682(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-metho...)
Affinity DataKi:  75nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212682(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-metho...)
Affinity DataIC50:  108nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed